CBD for Psychosis vs CBD Oil for Schizophrenia: Breaking News…

Is CBD Oil Good for Schizophrenia Can Psychosis Be Cured

Cannabidiol-based medicine has been seeing a huge surge in popularity for various reasons. Every day, people are finding the benefits of CBD and how it can affect their daily lives. People are now taking CBD for anxiety, stress relief, proper pain medication, and to help fight addiction. Multiple research papers have come out showing the everyday value of CBD. Through these papers, the world is learning about new diseases that CBD can address and the symptoms from different ailments that it can alleviate.


In this article, we are going to take a closer look at CBD for treating psychosis and schizophrenia. This has been making waves in the prescription drug market; using cannabis forms to treat various aspects of the disease shows that CBD will be capable of handling major problems in the future, but for now, we’ll stick to conventional schizophrenia treatment.


The progress of research


Research shows that using cannabis for psychotic symptoms may be possible. High-level CBD can help manage symptoms of psychosis that come from schizophrenia. It also helps deal with cognitive impairments and THC-induced psychotic symptoms, as well. Almost 90% of people who suffer from schizophrenia have cognitive deficits, and taking CBD will help them with cognitive impairments. Because the drugs on the market offer little to no help dealing with the cognitive deficits, CBD shows excellent signs of responding to the symptoms.


Is CBD Good for Schizophrenia: What Does the Study Show?


CBD actually having some sort of effect on symptoms of schizophrenia might open new doors to schizophrenia treatment in the future. While so many people are learning about CBD and its benefits now, CBD was used to treat various symptoms related to schizophrenia dating back to 1995. In that year, a study was published by Zuardi and his research team showing the diagnosis of a 19-year-old patient with schizophrenia. The patient was given 1500 mg of CBD every single day. At the end of the study, the patient reportedly showed massive changes, including significant improvement to the psychotic symptoms.


When it comes to research on this subject, there are plenty of articles and reports that have been published showing significant credibility that CBD can help deal with schizophrenia symptoms. In a study from 2006, the patients who were given 400 mg of CBD for four weeks. The psychotic symptoms were shown to improve in the patients.

The Results

Looking back at all the research on this subject, you will find plenty of examples and reports showing CBD to be one of the best ways to treat psychosis symptoms related to schizophrenia. Not all research shares the same outcome: some papers show that cannabidiol reduces psychosis symptoms by increasing the patient’s brain activity. CBD has been very effective against symptoms of schizophrenia; it also showed signs of improving mental conditions. That is why the drug is being used to treat anxiety, stress, and pain-related side effects, which often accompany terminal illnesses.

Can CBD Cause Psychosis?

A new study has shown that CBD alters brain activity in people with psychosis during memory tasks.
For the first time, the brains of people with the diagnosis of psychosis who have taken CBD have been scanned, providing important insight into which areas of the brain CBD targets.

Published in Psychological Medicine, the researchers used fMRI scans to examine the brain activity of 13 people with a diagnosis of psychosis under the influence of a single dose of CBD or placebo and 16 controls whilst they were undertaking a memory task.

Best CBD Oil For Psychosis

The study concluded that CBD is as effective as amisulpride in treating psychotic symptoms and has fewer adverse effects, including less extra pyramidal symptoms and weight gain. More recently, the effects of CBD on psychosis were explored in two double-blind randomized placebo-controlled clinical trials.

CBD Oil With Antipsychotics

Studies found that CBD had a beneficial, but modest, impact on positive psychotic symptoms and severity of illness when delivered as an adjunctive treatment to existing antipsychotic treatment. They also reported an improvement to cognition and the impact of patients’ illness on their day-to-day lives, which although only approaching statistical significance, may suggest a possible beneficial effect. However, they found no impact on negative psychotic symptoms.

Overall, these results suggest that CBD has an antipsychotic effect in schizophrenia when delivered as an adjunct treatment. However, this effect appears to be very modest and limited to only positive psychotic symptoms.

An Ongoing Process

Research certainly hasn’t stopped: the body of evidence continues to grow. Eventually, we may see more benefits of CBD related to diseases we deal with daily. So far, the therapeutic properties have been helpful. If research is anything to go by, we might see more development for CBD as time goes by, given that public interest has shown no signs of slowing down any time soon. This growing public interest will lead more companies into the market, releasing new products for a variety of issues. While the hype surrounding CBD may be overwhelming if you look at the sheer amount of research on its benefits, the excitement around this drug entering the market or potentially being used for more symptoms from terminal illnesses is understandable.


The Concern

But we should take all of this with a grain of salt. We know that CBD responds well to symptoms of diseases, but using it regularly can put a strain on your body. Research is still underway around the world. The FDA has been very strict on the regulation of CBD in the United States; they even banned any food and beverages from adding in CBD. That is why you see so many regulations on CBD and any product infused with CBD.

Though studies are still underway, we may see cannabis may become the leading choice for treating schizophrenia. However, getting a prescription for the drug will be the way to go if you want to take CBD to address schizophrenia-related psychosis. The ratio of THC to CBD has increased significantly over the past decade. This has opened up more value-based information about CBD and its effect on patients. At the same time, we saw plenty of side effects from these newfound CBDs.

CBD and Antipsychotic

This study found that CBD appears to help improve positive psychotic symptoms and patient wellness. However, this is one of the first trials in this cohort. Secondly, the benefits seen in this trial are modest while the other trial failed to find an effect, suggesting that CBD as an adjunct treatment provides at most a small benefit. This trial should be seen as providing early evidence that CBD could be modestly beneficial as an adjunct treatment to current antipsychotic medication. However, more evidence from large, well designed trials is required before any recommendations for clinical practice can be made.

Risperidone and CBD

Several studies suggest a strong association between schizophrenia and the endocannabinoid system. This system mediates e.g. the pro-psychotic effects of the best-known ingredient of the cannabis plant – delta-tetrahydrocannabinol (Δ9-THC). While the pro-psychotic Δ9-THC is known to abet the onset of schizophrenia, another, non-psychotomimetic plant ingredient – cannabidiol – has recently been shown to exert antipsychotic effects similar to those of one of the most effective modern antipsychotics, amisulpride, but it induced significantly less side effects.


Research shows that CBD can help patients suffering from schizophrenia. Given the number of studies done on CBD for schizophrenia, all signs indicate that this is indeed true. If you want to take CBD to treat your psychosis, you must consult your doctor first. Lack of research means that everyone should use precaution in using the drug.

Azriel Adelberg
About Azriel Adelberg

MSc Chemistry, University of California, Berkeley An Israeli born organic chemist and PROUD University of California, Berkeley graduate.

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